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Response Criteria in Advanced Systemic Mastocytosis: Evolution in the Era of KIT Inhibitors

Systemic mastocytosis (SM) is a rare clonal hematologic neoplasm, driven, in almost all cases, by the activating KIT D816V mutation that leads to the growth and accumulation of neoplastic mast cells. While patients with advanced forms of SM have a poor prognosis, the introduction of KIT inhibitors (...

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Detalles Bibliográficos
Autores principales: Shomali, William, Gotlib, Jason
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001403/
https://www.ncbi.nlm.nih.gov/pubmed/33804174
http://dx.doi.org/10.3390/ijms22062983