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The Effect of a TLR4 Agonist/Cationic Liposome Adjuvant on Varicella-Zoster Virus Glycoprotein E Vaccine Efficacy: Antigen Presentation, Uptake, and Delivery to Lymph Nodes

Adjuvant CIA09, composed of 1,2-dioleoyl-3-trimethylammonium-propane (DOTAP)-based cationic liposomes and the toll-like receptor 4 agonist de-O-acylated lipooligosaccharide (dLOS), has been shown to enhance antibody and cellular immune responses to varicella-zoster virus (VZV) glycoprotein E (gE), r...

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Detalles Bibliográficos
Autores principales: Wui, Seo Ri, Ko, Ara, Ryu, Ji In, Sim, Eojin, Lim, Soo Jeong, Park, Shin Ae, Kim, Kwang Sung, Kim, Ha, Youn, Hyewon, Lee, Na Gyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001429/
https://www.ncbi.nlm.nih.gov/pubmed/33804176
http://dx.doi.org/10.3390/pharmaceutics13030390