Cyclosporine Lipid Nanocapsules as Thermoresponsive Gel for Dry Eye Management: Promising Corneal Mucoadhesion, Biodistribution and Preclinical Efficacy in Rabbits

An ophthalmic cyclosporine (CsA) formulation based on Lipid nanocapsules (LNC) was developed for dry eye management, aiming to provide targeting to ocular tissues with long-term drug levels and maximum tolerability. CsA-LNC were of small particle size (41.9 ± 4.0 nm), narrow size distribution (PdI ≤...

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Detalles Bibliográficos
Autores principales: Eldesouky, Lubna M., El-Moslemany, Riham M., Ramadan, Alyaa A., Morsi, Mahmoud H., Khalafallah, Nawal M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001470/
https://www.ncbi.nlm.nih.gov/pubmed/33803242
http://dx.doi.org/10.3390/pharmaceutics13030360

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001470/
https://www.ncbi.nlm.nih.gov/pubmed/33803242
http://dx.doi.org/10.3390/pharmaceutics13030360

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