Detection of Rare Germline Variants in the Genomes of Patients with B-Cell Neoplasms

SIMPLE SUMMARY: The global importance of rare variants in tumorigenesis has been addressed by some pan-cancer analysis, revealing significant enrichments in protein-truncating variants affecting genes such as ATM, BRCA1/2, BRIP1, and MSH6. Germline variants can influence treatment response and contr...

Descripción completa

Detalles Bibliográficos
Autores principales: Mosquera Orgueira, Adrián, Cid López, Miguel, Peleteiro Raíndo, Andrés, Díaz Arias, José Ángel, Antelo Rodríguez, Beatriz, Bao Pérez, Laura, Alonso Vence, Natalia, Bendaña López, Ángeles, Abuin Blanco, Aitor, Melero Valentín, Paula, Ferreiro Ferro, Roi, Aliste Santos, Carlos, Fraga Rodríguez, Máximo Francisco, González Pérez, Marta Sonia, Pérez Encinas, Manuel Mateo, Bello López, José Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001490/
https://www.ncbi.nlm.nih.gov/pubmed/33809641
http://dx.doi.org/10.3390/cancers13061340

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001490/
https://www.ncbi.nlm.nih.gov/pubmed/33809641
http://dx.doi.org/10.3390/cancers13061340

Ejemplares similares