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Synthesis, Structural and Pharmacological Characterizations of CIC, a Novel α-Conotoxin with an Extended N-Terminal Tail

Cone snails are venomous marine predators that rely on fast-acting venom to subdue their prey and defend against aggressors. The conotoxins produced in the venom gland are small disulfide-rich peptides with high affinity and selectivity for their pharmacological targets. A dominant group comprises α...

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Detalles Bibliográficos
Autores principales: Giribaldi, Julien, Haufe, Yves, Evans, Edward R. J., Wilson, David T., Daly, Norelle L., Enjalbal, Christine, Nicke, Annette, Dutertre, Sébastien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001506/
https://www.ncbi.nlm.nih.gov/pubmed/33801301
http://dx.doi.org/10.3390/md19030141