CTRP9 Enhances Efferocytosis in Macrophages via MAPK/Drp1-Mediated Mitochondrial Fission and AdipoR1-Induced Immunometabolism

BACKGROUND: Clearance of apoptotic cells (ACs) by phagocytes (efferocytosis) suppresses post-apoptotic necrosis and alleviates inflammation. Defective efferocytosis induces diseases that include atherosclerosis and autoimmune diseases. C1q/TNF-related protein 9 (CTRP9), a novel adipokine, has been r...

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Detalles Bibliográficos
Autores principales: Song, Cheng-Xiang, Chen, Ji-Ying, Li, Na, Guo, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001589/
https://www.ncbi.nlm.nih.gov/pubmed/33790616
http://dx.doi.org/10.2147/JIR.S302944

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001589/
https://www.ncbi.nlm.nih.gov/pubmed/33790616
http://dx.doi.org/10.2147/JIR.S302944

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