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Addressing Antiretroviral Drug Resistance with Host-Targeting Drugs—First Steps towards Developing a Host-Targeting HIV-1 Assembly Inhibitor

The concerning increase in HIV-1 resistance argues for prioritizing the development of host-targeting antiviral drugs because such drugs can offer high genetic barriers to the selection of drug-resistant viral variants. Targeting host proteins could also yield drugs that act on viral life cycle even...

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Detalles Bibliográficos
Autores principales: Lingappa, Jaisri R., Lingappa, Vishwanath R., Reed, Jonathan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001593/
https://www.ncbi.nlm.nih.gov/pubmed/33802145
http://dx.doi.org/10.3390/v13030451