Cargando…

Characteristics of MSCs in Synovial Fluid and Mode of Action of Intra-Articular Injections of Synovial MSCs in Knee Osteoarthritis

We have been studying mesenchymal stem cells (MSCs) in synovial fluid and the intra-articular injection of synovial MSCs in osteoarthritis (OA) knees. Here, mainly based on our own findings, we overview the characteristics of endogenous MSCs in the synovial fluid of OA knees and their mode of action...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sekiya, Ichiro, Katano, Hisako, Ozeki, Nobutake
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Commentary
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001624/ https://www.ncbi.nlm.nih.gov/pubmed/33799588 http://dx.doi.org/10.3390/ijms22062838

Ejemplares similares

Cell membrane fluidity and ROS resistance define DMSO tolerance of cryopreserved synovial MSCs and HUVECs
por: Mizuno, Mitsuru, et al.
Publicado: (2022)

Thawed cryopreserved synovial mesenchymal stem cells show comparable effects to cultured cells in the inhibition of osteoarthritis progression in rats
por: Horiuchi, Kiyotaka, et al.
Publicado: (2021)

Ultrasound-Guided Harvesting of Synovium for Regenerative Medicine of Cartilage and Meniscus Using Synovial Mesenchymal Stem Cells
por: Ozeki, Nobutake, et al.
Publicado: (2021)

TNFα promotes proliferation of human synovial MSCs while maintaining chondrogenic potential
por: Shioda, Mikio, et al.
Publicado: (2017)

Changes in synovial fluid biomarkers and clinical efficacy of intra-articular injections of hyaluronic acid for patients with knee osteoarthritis
por: Kusayama, Yoshihiro, et al.
Publicado: (2014)

Attenuation of osteoarthritis progression through intra-articular injection of a combination of synovial membrane-derived MSCs (SMMSCs), platelet-rich plasma (PRP) and conditioned medium (secretome)
por: Nabavizadeh, Sara Sadat, et al.
Publicado: (2022)

Cryopreservation in 95% serum with 5% DMSO maintains colony formation and chondrogenic abilities in human synovial mesenchymal stem cells
por: Fujisawa, Ryota, et al.
Publicado: (2019)

Human synovial mesenchymal stem cells show time-dependent morphological changes and increased adhesion to degenerated porcine cartilage
por: Tanimoto, Takahiro, et al.
Publicado: (2022)

Synovial mesenchymal stem cells promote the meniscus repair in a novel pig meniscus injury model
por: Ozeki, Nobutake, et al.
Publicado: (2020)

Transplantation of human autologous synovial mesenchymal stem cells with trisomy 7 into the knee joint and 5 years of follow‐up
por: Mizuno, Mitsuru, et al.
Publicado: (2021)

Optimal Pore Size of Honeycomb Polylactic Acid Films for In Vitro Cartilage Formation by Synovial Mesenchymal Stem Cells
por: Yagi, Misaki, et al.
Publicado: (2021)

Intra-articular synovial lipoma of the knee joint
por: Poorteman, L, et al.
Publicado: (2015)

Yields and chondrogenic potential of primary synovial mesenchymal stem cells are comparable between rheumatoid arthritis and osteoarthritis patients
por: Kohno, Yuji, et al.
Publicado: (2017)

Comparison of adhesion of thawed and cultured synovial mesenchymal stem cells to the porcine meniscus and the relevance of cell surface microspikes
por: Fujii, Shunichi, et al.
Publicado: (2022)

Petaloid recombinant peptide enhances in vitro cartilage formation by synovial mesenchymal stem cells
por: Naritomi, Mana, et al.
Publicado: (2018)

Alterations in cartilage quantification before and after injections of mesenchymal stem cells into osteoarthritic knees
por: Sekiya, Ichiro, et al.
Publicado: (2021)

Three-dimensional MRI shows cartilage defect extension with no separation from the meniscus in women in their 70 s with knee osteoarthritis
por: Katano, Hisako, et al.
Publicado: (2022)

Additional Use of Synovial Mesenchymal Stem Cell Transplantation Following Surgical Repair of a Complex Degenerative Tear of the Medial Meniscus of the Knee: A Case Report
por: Sekiya, Ichiro, et al.
Publicado: (2019)

Tropoelastin improves adhesion and migration of intra-articular injected infrapatellar fat pad MSCs and reduces osteoarthritis progression()
por: Yang, Junjun, et al.
Publicado: (2021)

Complete human serum maintains viability and chondrogenic potential of human synovial stem cells: suitable conditions for transplantation
por: Mizuno, Mitsuru, et al.
Publicado: (2017)

Specific markers and properties of synovial mesenchymal stem cells in the surface, stromal, and perivascular regions
por: Mizuno, Mitsuru, et al.
Publicado: (2018)

Synovial Articular Inflammation of the Knee
Publicado: (1852)

Platelet-derived growth factor (PDGF)-AA/AB in human serum are potential indicators of the proliferative capacity of human synovial mesenchymal stem cells
por: Mizuno, Mitsuru, et al.
Publicado: (2015)

Degenerative Meniscus in Knee Osteoarthritis: From Pathology to Treatment
por: Ozeki, Nobutake, et al.
Publicado: (2022)

Does intra-articular fracture change the lubricant content of synovial fluid?
por: Ceylan, Hasan H., et al.
Publicado: (2015)

Repair of articular cartilage defects with intra-articular injection of autologous rabbit synovial fluid-derived mesenchymal stem cells
por: Jia, Zhaofeng, et al.
Publicado: (2018)

Changes in concentrations of haemostatic and inflammatory biomarkers in synovial fluid after intra-articular injection of lipopolysaccharide in horses
por: Andreassen, Stine Mandrup, et al.
Publicado: (2017)

Biomechanical analysis of a centralization procedure for extruded lateral meniscus after meniscectomy in porcine knee joints
por: Kohno, Yuji, et al.
Publicado: (2021)

Intra-Articular Giant Synovial Osteochondroma: Case Reports of the Ankle and Knee Joint
por: Fornaciari, Paolo, et al.
Publicado: (2015)

Bilateral synovial chondromatosis in the knee joint with both intra and extra-articular diseases
por: Bassir, Rida-Allah, et al.
Publicado: (2014)

Intra-articular Synovial Hemangioma: A Rare Cause of Knee Pain and Swelling
por: Abdulwahab, Ahmed D., et al.
Publicado: (2021)

The concentration of lidocaine and mepivacaine measured in synovial fluid of different joints of horses after single intra-articular injection
por: Adler, Ditte M. T., et al.
Publicado: (2022)

Synovial fluid proteome changes in ACL injury-induced posttraumatic osteoarthritis: Proteomics analysis of porcine knee synovial fluid
por: Kiapour, Ata M., et al.
Publicado: (2019)

Association of AI-determined Kellgren–Lawrence grade with medial meniscus extrusion and cartilage thickness by AI-based 3D MRI analysis in early knee osteoarthritis
por: Sekiya, Ichiro, et al.
Publicado: (2023)

Baker's cyst with extra‐ and intra‐articular synovial chondromatosis of knee: A case report
por: Khadka, Sushant Kumar, et al.
Publicado: (2023)

The effect of a centralization procedure for extruded lateral meniscus on load distribution in porcine knee joints at different flexion angles
por: Kubota, Rei, et al.
Publicado: (2020)

Intra-articular injection of recombinant TRAIL induces synovial apoptosis and reduces inflammation in a rabbit knee model of arthritis
por: Yao, Qingping, et al.
Publicado: (2006)

Expression of hypoxia-inducible factor-1α in synovial fluid and articular cartilage is associated with disease severity in knee osteoarthritis
por: Qing, Liming, et al.
Publicado: (2017)

Significant synovial pathology in a meniscectomy model of osteoarthritis: modification by intra-articular hyaluronan therapy
por: Smith, M. M., et al.
Publicado: (2008)

Two Discrete Intra-articular Synovial Hemangiomas of a Knee Joint Presenting as Chronic Knee Pain
por: Jain, Mantu, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_jk91as5k6pjk2dhr4rn6bm3o9o