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Epitope Binning of Novel Monoclonal Anti F1 and Anti LcrV Antibodies and Their Application in a Simple, Short, HTRF Test for Clinical Plague Detection

Mouse monoclonal antibodies were raised against plague disease biomarkers: the bacterial capsular protein fraction 1 (F1) and the low-calcium response—LcrV virulence factor (Vag). A novel tandem assay, employing BioLayer Interferometry (BLI), enabled the isolation of antibodies against four differen...

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Detalles Bibliográficos
Autores principales: Mechaly, Adva, Vitner, Einat B., Levy, Yinon, Gur, David, Barlev-Gross, Moria, Sittner, Assa, Koren, Michal, Levy, Haim, Mamroud, Emanuelle, Fisher, Morly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001648/
https://www.ncbi.nlm.nih.gov/pubmed/33801490
http://dx.doi.org/10.3390/pathogens10030285