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Myocardium-Specific Deletion of Rac1 Causes Ventricular Noncompaction and Outflow Tract Defects

Background: Left ventricular noncompaction (LVNC) is a cardiomyopathy that can lead to arrhythmias, embolic events and heart failure. Despite our current knowledge of cardiac development, the mechanisms underlying noncompaction of the ventricular myocardium are still poorly understood. The small GTP...

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Detalles Bibliográficos
Autores principales: Leung, Carmen, Engineer, Anish, Kim, Mella Y., Lu, Xiangru, Feng, Qingping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001666/
https://www.ncbi.nlm.nih.gov/pubmed/33804107
http://dx.doi.org/10.3390/jcdd8030029