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Pan-Cancer Analysis of Human Kinome Gene Expression and Promoter DNA Methylation Identifies Dark Kinase Biomarkers in Multiple Cancers
SIMPLE SUMMARY: Due to their central role in many biological processes, studies on protein kinases are an area of active research. In the last few decades, several inhibitors that target kinases have been approved by U.S. Food and Drug Administration (FDA). However, a large proportion of kinases rem...
Autores principales: | Southekal, Siddesh, Mishra, Nitish Kumar, Guda, Chittibabu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001681/ https://www.ncbi.nlm.nih.gov/pubmed/33801837 http://dx.doi.org/10.3390/cancers13061189 |
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