Cross-Disorder Analysis of De Novo Variants Increases the Power of Prioritising Candidate Genes

De novo variants (DNVs) are critical to the treatment of neurodevelopmental disorders (NDDs). However, effectively identifying candidate genes in small cohorts is challenging in most NDDs because of high genetic heterogeneity. We hypothesised that integrating DNVs from multiple NDDs with genetic sim...

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Detalles Bibliográficos
Autores principales: Li, Kuokuo, Ling, Zhengbao, Luo, Tengfei, Zhao, Guihu, Zhou, Qiao, Wang, Xiaomeng, Xia, Kun, Li, Jinchen, Li, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001830/
https://www.ncbi.nlm.nih.gov/pubmed/33809095
http://dx.doi.org/10.3390/life11030233

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001830/
https://www.ncbi.nlm.nih.gov/pubmed/33809095
http://dx.doi.org/10.3390/life11030233

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