Synthesis of Piperidine Nucleosides as Conformationally Restricted Immucillin Mimics

The de novo synthesis of piperidine nucleosides from our homologating agent 5,6-dihydro-1,4-dithiin is herein reported. The structure and conformation of nucleosides were conceived to faithfully resemble the well-known nucleoside drugs Immucillins H and A in their bioactive conformation. NMR analysi...

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Detalles Bibliográficos
Autores principales: De Fenza, Maria, Esposito, Anna, D’Alonzo, Daniele, Guaragna, Annalisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001838/
https://www.ncbi.nlm.nih.gov/pubmed/33809603
http://dx.doi.org/10.3390/molecules26061652

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001838/
https://www.ncbi.nlm.nih.gov/pubmed/33809603
http://dx.doi.org/10.3390/molecules26061652

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