Cargando…
Synthesis of Piperidine Nucleosides as Conformationally Restricted Immucillin Mimics
The de novo synthesis of piperidine nucleosides from our homologating agent 5,6-dihydro-1,4-dithiin is herein reported. The structure and conformation of nucleosides were conceived to faithfully resemble the well-known nucleoside drugs Immucillins H and A in their bioactive conformation. NMR analysi...
Autores principales: | De Fenza, Maria, Esposito, Anna, D’Alonzo, Daniele, Guaragna, Annalisa |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001838/ https://www.ncbi.nlm.nih.gov/pubmed/33809603 http://dx.doi.org/10.3390/molecules26061652 |
Ejemplares similares
-
Expeditious synthesis and preliminary antimicrobial activity of deflazacort and its precursors
por: Esposito, Anna, et al.
Publicado: (2019) -
Synthesis and Therapeutic Applications of Iminosugars in Cystic Fibrosis
por: Esposito, Anna, et al.
Publicado: (2020) -
Toward the Identification of Novel Antimicrobial Agents: One-Pot Synthesis of Lipophilic Conjugates of N-Alkyl d- and l-Iminosugars
por: Esposito, Anna, et al.
Publicado: (2020) -
N-Nonyloxypentyl-l-Deoxynojirimycin Inhibits Growth, Biofilm Formation and Virulence Factors Expression of Staphylococcus aureus
por: De Gregorio, Eliana, et al.
Publicado: (2020) -
Antibacterial and Antivirulence Activity of Glucocorticoid PYED-1 against Stenotrophomonas maltophilia
por: Esposito, Anna, et al.
Publicado: (2020)