Aerosolized In Vivo 3D Localization of Nose-to-Brain Nanocarrier Delivery Using Multimodality Neuroimaging in a Rat Model—Protocol Development

The fate of intranasal aerosolized radiolabeled polymeric micellar nanoparticles (LPNPs) was tracked with positron emission tomography/computer tomography (PET/CT) imaging in a rat model to measure nose-to-brain delivery. A quantitative temporal and spatial testing protocol for new radio-nanotherano...

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Detalles Bibliográficos
Autores principales: Veronesi, Michael C., Graner, Brian D., Cheng, Shih-Hsun, Zamora, Marta, Zarrinmayeh, Hamideh, Chen, Chin-Tu, Das, Sudip K., Vannier, Michael W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001876/
https://www.ncbi.nlm.nih.gov/pubmed/33804222
http://dx.doi.org/10.3390/pharmaceutics13030391

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001876/
https://www.ncbi.nlm.nih.gov/pubmed/33804222
http://dx.doi.org/10.3390/pharmaceutics13030391

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