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Aerosolized In Vivo 3D Localization of Nose-to-Brain Nanocarrier Delivery Using Multimodality Neuroimaging in a Rat Model—Protocol Development
The fate of intranasal aerosolized radiolabeled polymeric micellar nanoparticles (LPNPs) was tracked with positron emission tomography/computer tomography (PET/CT) imaging in a rat model to measure nose-to-brain delivery. A quantitative temporal and spatial testing protocol for new radio-nanotherano...
Autores principales: | Veronesi, Michael C., Graner, Brian D., Cheng, Shih-Hsun, Zamora, Marta, Zarrinmayeh, Hamideh, Chen, Chin-Tu, Das, Sudip K., Vannier, Michael W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001876/ https://www.ncbi.nlm.nih.gov/pubmed/33804222 http://dx.doi.org/10.3390/pharmaceutics13030391 |
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