Ivabradine Induces Cardiac Protection against Myocardial Infarction by Preventing Cyclophilin-A Secretion in Pigs under Coronary Ischemia/Reperfusion

In response to cardiac ischemia/reperfusion, proteolysis mediated by extracellular matrix metalloproteinase inducer (EMMPRIN) and its secreted ligand cyclophilin-A (CyPA) significantly contributes to cardiac injury and necrosis. Here, we aimed to investigate if, in addition to the effect on the funn...

Descripción completa

Detalles Bibliográficos
Autores principales: Hernandez, Ignacio, Tesoro, Laura, Ramirez-Carracedo, Rafael, Diez-Mata, Javier, Sanchez, Sandra, Saura, Marta, Zamorano, Jose Luis, Zaragoza, Carlos, Botana, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001911/
https://www.ncbi.nlm.nih.gov/pubmed/33809359
http://dx.doi.org/10.3390/ijms22062902

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001911/
https://www.ncbi.nlm.nih.gov/pubmed/33809359
http://dx.doi.org/10.3390/ijms22062902

Ejemplares similares