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Ivabradine Induces Cardiac Protection against Myocardial Infarction by Preventing Cyclophilin-A Secretion in Pigs under Coronary Ischemia/Reperfusion

In response to cardiac ischemia/reperfusion, proteolysis mediated by extracellular matrix metalloproteinase inducer (EMMPRIN) and its secreted ligand cyclophilin-A (CyPA) significantly contributes to cardiac injury and necrosis. Here, we aimed to investigate if, in addition to the effect on the funn...

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Detalles Bibliográficos
Autores principales:	Hernandez, Ignacio, Tesoro, Laura, Ramirez-Carracedo, Rafael, Diez-Mata, Javier, Sanchez, Sandra, Saura, Marta, Zamorano, Jose Luis, Zaragoza, Carlos, Botana, Laura
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001911/ https://www.ncbi.nlm.nih.gov/pubmed/33809359 http://dx.doi.org/10.3390/ijms22062902

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