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Applicability of an Experimental Grade of Hydroxypropyl Methylcellulose Acetate Succinate as a Carrier for Formation of Solid Dispersion with Indomethacin

The transformation of a crystalline drug into an amorphous form is a promising way to enhance the oral bioavailability of poorly water-soluble drugs. Blending of a carrier, such as a hydrophilic polymer, with an amorphous drug is a widely used method to produce a solid dispersion and inhibit crystal...

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Detalles Bibliográficos
Autores principales: Ueda, Hiroshi, Hirakawa, Yuya, Tanaka, Hironori, Miyano, Tetsuya, Sugita, Katsuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001926/
https://www.ncbi.nlm.nih.gov/pubmed/33800229
http://dx.doi.org/10.3390/pharmaceutics13030353