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Applicability of an Experimental Grade of Hydroxypropyl Methylcellulose Acetate Succinate as a Carrier for Formation of Solid Dispersion with Indomethacin
The transformation of a crystalline drug into an amorphous form is a promising way to enhance the oral bioavailability of poorly water-soluble drugs. Blending of a carrier, such as a hydrophilic polymer, with an amorphous drug is a widely used method to produce a solid dispersion and inhibit crystal...
Autores principales: | Ueda, Hiroshi, Hirakawa, Yuya, Tanaka, Hironori, Miyano, Tetsuya, Sugita, Katsuji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001926/ https://www.ncbi.nlm.nih.gov/pubmed/33800229 http://dx.doi.org/10.3390/pharmaceutics13030353 |
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