Liposome-Imipramine Blue Inhibits Sonic Hedgehog Medulloblastoma In Vivo

SIMPLE SUMMARY: Imipramine blue (IB) is a novel NADPH oxidase inhibitor. We assessed the single agent activity of IB against a well-established model of medulloblastoma, the most common malignant brain tumor of childhood. IB slowed progression of medulloblastoma and increased survival of mice with t...

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Detalles Bibliográficos
Autores principales: MacDonald, Tobey J., Liu, Jingbo, Yu, Bing, Malhotra, Anshu, Munson, Jenny, Park, Jaekeun C., Wang, Kenty, Fei, Baowei, Bellamkonda, Ravi, Arbiser, Jack
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001973/
https://www.ncbi.nlm.nih.gov/pubmed/33799550
http://dx.doi.org/10.3390/cancers13061220

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001973/
https://www.ncbi.nlm.nih.gov/pubmed/33799550
http://dx.doi.org/10.3390/cancers13061220

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