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Liposome-Imipramine Blue Inhibits Sonic Hedgehog Medulloblastoma In Vivo
SIMPLE SUMMARY: Imipramine blue (IB) is a novel NADPH oxidase inhibitor. We assessed the single agent activity of IB against a well-established model of medulloblastoma, the most common malignant brain tumor of childhood. IB slowed progression of medulloblastoma and increased survival of mice with t...
Autores principales: | MacDonald, Tobey J., Liu, Jingbo, Yu, Bing, Malhotra, Anshu, Munson, Jenny, Park, Jaekeun C., Wang, Kenty, Fei, Baowei, Bellamkonda, Ravi, Arbiser, Jack |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001973/ https://www.ncbi.nlm.nih.gov/pubmed/33799550 http://dx.doi.org/10.3390/cancers13061220 |
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