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m(5)U54 tRNA Hypomodification by Lack of TRMT2A Drives the Generation of tRNA-Derived Small RNAs

Transfer RNA (tRNA) molecules contain various post-transcriptional modifications that are crucial for tRNA stability, translation efficiency, and fidelity. Besides their canonical roles in translation, tRNAs also originate tRNA-derived small RNAs (tsRNAs), a class of small non-coding RNAs with regul...

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Detalles Bibliográficos
Autores principales: Pereira, Marisa, Ribeiro, Diana R., Pinheiro, Miguel M., Ferreira, Margarida, Kellner, Stefanie, Soares, Ana R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8001983/
https://www.ncbi.nlm.nih.gov/pubmed/33799331
http://dx.doi.org/10.3390/ijms22062941