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Metabolic and Mitochondrial Functioning in Chimeric Antigen Receptor (CAR)—T Cells
SIMPLE SUMMARY: We review the mechanisms of cellular metabolism and mitochondrial function that have potential to impact on the success of chimeric antigen receptor (CAR) T cell therapy. The review focuses readers on mitochondrial functions to allow a better understanding of the complexity of T cell...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8002030/ https://www.ncbi.nlm.nih.gov/pubmed/33799768 http://dx.doi.org/10.3390/cancers13061229 |