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NHERF1/EBP50 as a Target for Modulation of MRP Function in HepG2 Cells

As increased expression and activities of efflux transporters (ETs) often cause drug resistance in cancers, we tried modulating ET activity in cancer cells, using scaffold proteins such as ezrin/radixin/moesin (ERM) proteins, and Na(+)/H(+) exchanger regulatory factor-1 (NHERF1)/ERM-binding phosphop...

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Detalles Bibliográficos
Autores principales: Kawase, Atsushi, Hirosoko, Miho, Sugihara, Yuka, Koyama, Yunosuke, Fukae, Ayaka, Shimada, Hiroaki, Iwaki, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8002045/
https://www.ncbi.nlm.nih.gov/pubmed/33800412
http://dx.doi.org/10.3390/ph14030239