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NHERF1/EBP50 as a Target for Modulation of MRP Function in HepG2 Cells
As increased expression and activities of efflux transporters (ETs) often cause drug resistance in cancers, we tried modulating ET activity in cancer cells, using scaffold proteins such as ezrin/radixin/moesin (ERM) proteins, and Na(+)/H(+) exchanger regulatory factor-1 (NHERF1)/ERM-binding phosphop...
Autores principales: | Kawase, Atsushi, Hirosoko, Miho, Sugihara, Yuka, Koyama, Yunosuke, Fukae, Ayaka, Shimada, Hiroaki, Iwaki, Masahiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8002045/ https://www.ncbi.nlm.nih.gov/pubmed/33800412 http://dx.doi.org/10.3390/ph14030239 |
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