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Properties of Oligomeric Interaction of the Cytomegalovirus Core Nuclear Egress Complex (NEC) and Its Sensitivity to an NEC Inhibitory Small Molecule

Herpesviral nuclear egress is a regulated process shared by all family members, ensuring the efficient cytoplasmic release of viral capsids. In the case of human cytomegalovirus (HCMV), the core of the nuclear egress complex (NEC) consists of the pUL50-pUL53 heterodimer that builds hexameric lattice...

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Detalles Bibliográficos
Autores principales: Kicuntod, Jintawee, Alkhashrom, Sewar, Häge, Sigrun, Diewald, Benedikt, Müller, Regina, Hahn, Friedrich, Lischka, Peter, Sticht, Heinrich, Eichler, Jutta, Marschall, Manfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8002134/
https://www.ncbi.nlm.nih.gov/pubmed/33799898
http://dx.doi.org/10.3390/v13030462