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Tyrosine Kinase Inhibitors Are Promising Therapeutic Tools for Cats with HER2-Positive Mammary Carcinoma

Feline mammary carcinoma (FMC) is a common neoplasia in cat, being HER2-positive the most prevalent subtype. In woman’s breast cancer, tyrosine kinase inhibitors (TKi) are used as a therapeutic option, by blocking the phosphorylation of the HER2 tyrosine kinase domain. Moreover, clinical trials demo...

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Detalles Bibliográficos
Autores principales: Gameiro, Andreia, Almeida, Filipe, Nascimento, Catarina, Correia, Jorge, Ferreira, Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8002158/
https://www.ncbi.nlm.nih.gov/pubmed/33800900
http://dx.doi.org/10.3390/pharmaceutics13030346