Structural Polymorphism of Sorafenib Tosylate as a Key Factor in Its Solubility Differentiation

The presence of active pharmaceutical ingredients (APIs) in the forms of different polymorphic states can induce differences in their physicochemical properties. In the case of poorly soluble APIs, like the oncological drug sorafenib tosylate, small variations in solubility may result in large bioav...

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Detalles Bibliográficos
Autores principales: Wiergowska, Gabriela, Stasiłowicz, Anna, Miklaszewski, Andrzej, Lewandowska, Kornelia, Cielecka-Piontek, Judyta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8002161/
https://www.ncbi.nlm.nih.gov/pubmed/33805754
http://dx.doi.org/10.3390/pharmaceutics13030384

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8002161/
https://www.ncbi.nlm.nih.gov/pubmed/33805754
http://dx.doi.org/10.3390/pharmaceutics13030384

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