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Bioinformatic Analysis of the Nicotinamide Binding Site in Poly(ADP-Ribose) Polymerase Family Proteins

SIMPLE SUMMARY: The PARP family consists of 17 proteins, and some of them are responsible for cancer cells’ viability. Much attention is therefore given to the search for chemical compounds with the ability to suppress distinct PARP family members (for example, PARP-5a and 5b). Here, we present the...

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Detalles Bibliográficos
Autores principales: Manasaryan, Garri, Suplatov, Dmitry, Pushkarev, Sergey, Drobot, Viktor, Kuimov, Alexander, Švedas, Vytas, Nilov, Dmitry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8002165/
https://www.ncbi.nlm.nih.gov/pubmed/33801950
http://dx.doi.org/10.3390/cancers13061201