Exons and introns exhibit transcriptional strand asymmetry of dinucleotide distribution, damage formation and DNA repair

Recent cancer sequencing efforts have uncovered asymmetry in DNA damage induced mutagenesis between the transcribed and non-transcribed strands of genes. Here, we investigate the major type of damage induced by ultraviolet (UV) radiation, the cyclobutane pyrimidine dimers (CPDs), which are formed pr...

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Detalles Bibliográficos
Autores principales: Heilbrun, Elisheva E, Merav, May, Adar, Sheera
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Standard Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8002178/
https://www.ncbi.nlm.nih.gov/pubmed/33817640
http://dx.doi.org/10.1093/nargab/lqab020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8002178/
https://www.ncbi.nlm.nih.gov/pubmed/33817640
http://dx.doi.org/10.1093/nargab/lqab020

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