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Exons and introns exhibit transcriptional strand asymmetry of dinucleotide distribution, damage formation and DNA repair
Recent cancer sequencing efforts have uncovered asymmetry in DNA damage induced mutagenesis between the transcribed and non-transcribed strands of genes. Here, we investigate the major type of damage induced by ultraviolet (UV) radiation, the cyclobutane pyrimidine dimers (CPDs), which are formed pr...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8002178/ https://www.ncbi.nlm.nih.gov/pubmed/33817640 http://dx.doi.org/10.1093/nargab/lqab020 |