Electronic Circular Dichroism of the Cas9 Protein and gRNA:Cas9 Ribonucleoprotein Complex

The Streptococcus pyogenes Cas9 protein (SpCas9), a component of CRISPR-based immune system in microbes, has become commonly utilized for genome editing. This nuclease forms a ribonucleoprotein (RNP) complex with guide RNA (gRNA) which induces Cas9 structural changes and triggers its cleavage activi...

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Detalles Bibliográficos
Autores principales: Halat, Monika, Klimek-Chodacka, Magdalena, Orleanska, Jagoda, Baranska, Malgorzata, Baranski, Rafal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8002190/
https://www.ncbi.nlm.nih.gov/pubmed/33805827
http://dx.doi.org/10.3390/ijms22062937

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8002190/
https://www.ncbi.nlm.nih.gov/pubmed/33805827
http://dx.doi.org/10.3390/ijms22062937

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