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CHPF Regulates the Aggressive Phenotypes of Hepatocellular Carcinoma Cells via the Modulation of the Decorin and TGF-β Pathways

SIMPLE SUMMARY: Altered extracellular chondroitin sulfate (CS) contributes to tumor progression in many cancers. CHPF is a key enzyme supporting the elongation of CS. Here we showed that CHPF was frequently downregulated in hepatocellular carcinoma (HCC) tumors compared with adjacent non-tumor tissu...

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Detalles Bibliográficos
Autores principales: Liu, Chiung-Hui, Wu, Bo-Rui, Ho, Ying-Jui, Chu, Yin-Hung, Hsu, Wei-Cheng, Tseng, To-Jung, Li, Ju-Pi, Liao, Wen-Chieh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8002199/
https://www.ncbi.nlm.nih.gov/pubmed/33809195
http://dx.doi.org/10.3390/cancers13061261