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Evaluation of a Novel Plasmid for Simultaneous Gene Electrotransfer-Mediated Silencing of CD105 and CD146 in Combination with Irradiation

Targeting tumor vasculature through specific endothelial cell markers represents a promising approach for cancer treatment. Here our aim was to construct an antibiotic resistance gene-free plasmid encoding shRNAs to simultaneously target two endothelial cell markers, CD105 and CD146, and to test its...

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Detalles Bibliográficos
Autores principales: Savarin, Monika, Kamensek, Urska, Znidar, Katarina, Todorovic, Vesna, Sersa, Gregor, Cemazar, Maja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8002395/
https://www.ncbi.nlm.nih.gov/pubmed/33802812
http://dx.doi.org/10.3390/ijms22063069