Cargando…
Evaluation of a Novel Plasmid for Simultaneous Gene Electrotransfer-Mediated Silencing of CD105 and CD146 in Combination with Irradiation
Targeting tumor vasculature through specific endothelial cell markers represents a promising approach for cancer treatment. Here our aim was to construct an antibiotic resistance gene-free plasmid encoding shRNAs to simultaneously target two endothelial cell markers, CD105 and CD146, and to test its...
Autores principales: | Savarin, Monika, Kamensek, Urska, Znidar, Katarina, Todorovic, Vesna, Sersa, Gregor, Cemazar, Maja |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8002395/ https://www.ncbi.nlm.nih.gov/pubmed/33802812 http://dx.doi.org/10.3390/ijms22063069 |
Ejemplares similares
-
Tumor Radiosensitization by Gene Electrotransfer-Mediated Double Targeting of Tumor Vasculature
por: Savarin, Monika, et al.
Publicado: (2023) -
Electrotransfer of plasmid DNA radiosensitizes B16F10 tumors through activation of immune response
por: Savarin, Monika, et al.
Publicado: (2017) -
Antitumor in situ vaccination effect of TNFα and IL-12 plasmid DNA electrotransfer in a murine melanoma model
por: Kamensek, Urska, et al.
Publicado: (2018) -
Electrotransfer of Different Control Plasmids Elicits Different Antitumor Effectiveness in B16.F10 Melanoma
por: Bosnjak, Masa, et al.
Publicado: (2018) -
Maintenance and gene electrotransfer efficiency of antibiotic resistance gene-free plasmids encoding mouse, canine and human interleukin-12 orthologues
por: Kamensek, Urska, et al.
Publicado: (2022)