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In Translation: FcRn across the Therapeutic Spectrum

As an essential modulator of IgG disposition, the neonatal Fc receptor (FcRn) governs the pharmacokinetics and functions many therapeutic modalities. In this review, we thoroughly reexamine the hitherto elucidated biological and thermodynamic properties of FcRn to provide context for our assessment...

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Detalles Bibliográficos
Autores principales: Qi, Timothy, Cao, Yanguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8002405/
https://www.ncbi.nlm.nih.gov/pubmed/33802650
http://dx.doi.org/10.3390/ijms22063048