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The Plasma Membrane Ca(2+) Pump PMCA4b Regulates Melanoma Cell Migration through Remodeling of the Actin Cytoskeleton

SIMPLE SUMMARY: Earlier we demonstrated that the plasma membrane Ca(2+) pump PMCA4b inhibits migration and metastatic activity of BRAF mutant melanoma cells, however, the exact mechanism has not been fully understood. Here we demonstrate that PMCA4b acted through actin cytoskeleton remodeling in gen...

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Detalles Bibliográficos
Autores principales: Naffa, Randa, Padányi, Rita, Ignácz, Attila, Hegyi, Zoltán, Jezsó, Bálint, Tóth, Sarolta, Varga, Karolina, Homolya, László, Hegedűs, Luca, Schlett, Katalin, Enyedi, Agnes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8002435/
https://www.ncbi.nlm.nih.gov/pubmed/33802790
http://dx.doi.org/10.3390/cancers13061354