Modulation of Tubular pH by Acetazolamide in a Ca(2+) Transport Deficient Mice Facilitates Calcium Nephrolithiasis

Proximal tubular (PT) acidosis, which alkalinizes the urinary filtrate, together with Ca(2+) supersaturation in PT can induce luminal calcium phosphate (CaP) crystal formation. While such CaP crystals are known to act as a nidus for CaP/calcium oxalate (CaOx) mixed stone formation, the regulation of...

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Detalles Bibliográficos
Autores principales: Awuah Boadi, Eugenia, Shin, Samuel, Yeroushalmi, Samuel, Choi, Bok-Eum, Li, Peijun, Bandyopadhyay, Bidhan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8002449/
https://www.ncbi.nlm.nih.gov/pubmed/33802660
http://dx.doi.org/10.3390/ijms22063050

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8002449/
https://www.ncbi.nlm.nih.gov/pubmed/33802660
http://dx.doi.org/10.3390/ijms22063050

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