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Modulation of Tubular pH by Acetazolamide in a Ca(2+) Transport Deficient Mice Facilitates Calcium Nephrolithiasis
Proximal tubular (PT) acidosis, which alkalinizes the urinary filtrate, together with Ca(2+) supersaturation in PT can induce luminal calcium phosphate (CaP) crystal formation. While such CaP crystals are known to act as a nidus for CaP/calcium oxalate (CaOx) mixed stone formation, the regulation of...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8002449/ https://www.ncbi.nlm.nih.gov/pubmed/33802660 http://dx.doi.org/10.3390/ijms22063050 |