IRE1α Is a Therapeutic Target for Cystic Fibrosis Airway Inflammation

New anti-inflammatory treatments are needed for CF airway disease. Studies have implicated the endoplasmic reticulum stress transducer inositol requiring enzyme 1α (IRE1α) in CF airway inflammation. The activation of IRE1α promotes activation of its cytoplasmic kinase and RNase, resulting in mRNA sp...

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Detalles Bibliográficos
Autores principales: Hull-Ryde, Emily A., Minges, John T., Martino, Mary E. B., Kato, Takafumi, Norris-Drouin, Jacqueline L., Ribeiro, Carla M. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8002512/
https://www.ncbi.nlm.nih.gov/pubmed/33802742
http://dx.doi.org/10.3390/ijms22063063

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8002512/
https://www.ncbi.nlm.nih.gov/pubmed/33802742
http://dx.doi.org/10.3390/ijms22063063

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