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A Comprehensive Approach to Compatibility Testing Using Chromatographic, Thermal and Spectroscopic Techniques: Evaluation of Potential for a Monolayer Fixed-Dose Combination of 6-Mercaptopurine and Folic Acid

In this work, a systematical compatibility investigation of 6-mercaptopurine and folic acid, two commonly used medications in the treatment of inflammatory bowel disease, for the needs of a fixed-dose combination development strategy is shown. Various techniques and approaches, such as differential...

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Detalles Bibliográficos
Autores principales: Brusač, Edvin, Jeličić, Mario-Livio, Cvetnić, Matija, Amidžić Klarić, Daniela, Nigović, Biljana, Mornar, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8002671/
https://www.ncbi.nlm.nih.gov/pubmed/33802871
http://dx.doi.org/10.3390/ph14030274