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Efficient Hydrolysis of Gluten-Derived Celiac Disease-Triggering Immunogenic Peptides by a Bacterial Serine Protease from Burkholderia gladioli

Celiac disease is an autoimmune disorder triggered by toxic peptides derived from incompletely digested glutens in the stomach. Peptidases that can digest the toxic peptides may formulate an oral enzyme therapy to improve the patients’ health condition. Bga1903 is a serine endopeptidase secreted by...

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Detalles Bibliográficos
Autores principales: Liu, Yu-You, Lee, Cheng-Cheng, Hsu, Jun-Hao, Leu, Wei-Ming, Meng, Menghsiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8002681/
https://www.ncbi.nlm.nih.gov/pubmed/33802942
http://dx.doi.org/10.3390/biom11030451