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Resurrection of a Viral Internal Ribosome Entry Site from a 700 Year Old Ancient Northwest Territories Cripavirus

The dicistrovirus intergenic region internal ribosome entry site (IGR IRES) uses an unprecedented, streamlined mechanism whereby the IRES adopts a triple-pseudoknot (PK) structure to directly bind to the conserved core of the ribosome and drive translation from a non-AUG codon. The origin of this IR...

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Detalles Bibliográficos
Autores principales: Wang, Xinying, Vlok, Marli, Flibotte, Stephane, Jan, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8002689/
https://www.ncbi.nlm.nih.gov/pubmed/33802878
http://dx.doi.org/10.3390/v13030493