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Identification of an Immature Subset of PMN-MDSC Correlated to Response to Checkpoint Inhibitor Therapy in Patients with Metastatic Melanoma

SIMPLE SUMMARY: Polymorphonuclear myeloid-derived suppressive cells (PMN-MDSCs) have been associated to bad prognosis and resistance to immune checkpoint inhibitor (ICI) therapy in metastatic melanoma (MM). In this study, we describe an immature subset of PMN-MDSCs capable of a high cytotoxicity aga...

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Detalles Bibliográficos
Autores principales: Gondois-Rey, Françoise, Paul, Magali, Alcaraz, Florence, Bourass, Sarah, Monnier, Jilliana, Malissen, Nausicaa, Grob, Jean-Jacques, Bruger, Annika M., Van Der Bruggen, Pierre, Gaudy-Marqueste, Caroline, Olive, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8002694/
https://www.ncbi.nlm.nih.gov/pubmed/33802925
http://dx.doi.org/10.3390/cancers13061362