The Ablation of VEGFR-1 Signaling Promotes Pressure Overload-Induced Cardiac Dysfunction and Sudden Death

Molecular mechanisms involved in cardiac remodelling are not fully understood. To study the role of vascular endothelial growth factor receptor 1 (VEGFR-1) signaling in left ventricular hypertrophy (LVH) and heart failure, we used a mouse model lacking the intracellular VEGFR-1 tyrosine kinase domai...

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Detalles Bibliográficos
Autores principales: Tirronen, Annakaisa, Downes, Nicholas L., Huusko, Jenni, Laakkonen, Johanna P., Tuomainen, Tomi, Tavi, Pasi, Hedman, Marja, Ylä-Herttuala, Seppo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8002705/
https://www.ncbi.nlm.nih.gov/pubmed/33802976
http://dx.doi.org/10.3390/biom11030452

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8002705/
https://www.ncbi.nlm.nih.gov/pubmed/33802976
http://dx.doi.org/10.3390/biom11030452

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