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Cell Surface GRP94 as a Novel Emerging Therapeutic Target for Monoclonal Antibody Cancer Therapy

Glucose-regulated protein 94 (GRP94) is an endoplasmic reticulum (ER)-resident member of the heat shock protein 90 (HSP90) family. In physiological conditions, it plays a vital role in regulating biological functions, including chaperoning cellular proteins in the ER lumen, maintaining calcium homeo...

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Detalles Bibliográficos
Autores principales: Kim, Ji Woong, Cho, Yea Bin, Lee, Sukmook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8002708/
https://www.ncbi.nlm.nih.gov/pubmed/33802964
http://dx.doi.org/10.3390/cells10030670