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RNA-seq Characterization of Melanoma Phenotype Switch in 3D Collagen after p38 MAPK Inhibitor Treatment

Melanoma phenotype plasticity underlies tumour dissemination and resistance to therapy, yet its regulation is incompletely understood. In vivo switching between a more differentiated, proliferative phenotype and a dedifferentiated, invasive phenotype is directed by the tumour microenvironment. We fo...

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Detalles Bibliográficos
Autores principales: Čermák, Vladimír, Škarková, Aneta, Merta, Ladislav, Kolomazníková, Veronika, Palušová, Veronika, Uldrijan, Stjepan, Rösel, Daniel, Brábek, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8002814/
https://www.ncbi.nlm.nih.gov/pubmed/33802847
http://dx.doi.org/10.3390/biom11030449