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Thermosensitive Gels Used to Improve Microneedle-Assisted Transdermal Delivery of Naltrexone

Transdermal delivery of naltrexone (NTX) can be enhanced using microneedles, although micropores generated this way can reseal by 48 h in humans, which prevents further drug delivery from a formulation. Poloxamer 407 (P407) is a thermosensitive polymer that may extend microneedle-assisted NTX delive...

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Detalles Bibliográficos
Autores principales: Tobin, Kevin V., Fiegel, Jennifer, Brogden, Nicole K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8002892/
https://www.ncbi.nlm.nih.gov/pubmed/33803552
http://dx.doi.org/10.3390/polym13060933