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Thermosensitive Gels Used to Improve Microneedle-Assisted Transdermal Delivery of Naltrexone
Transdermal delivery of naltrexone (NTX) can be enhanced using microneedles, although micropores generated this way can reseal by 48 h in humans, which prevents further drug delivery from a formulation. Poloxamer 407 (P407) is a thermosensitive polymer that may extend microneedle-assisted NTX delive...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8002892/ https://www.ncbi.nlm.nih.gov/pubmed/33803552 http://dx.doi.org/10.3390/polym13060933 |